In 2014, Rochester's Shawn Dunwoody created a mural on the Interstate 490 bridge over West Main Street. It depicts the abolitionist Frederick Douglass, as well as Susan B. Anthony, Nathaniel Rochester and Austin Steward - all famous Rochester figures

In 2008, muralist K. Fitch painted a mural of Frederick Douglass in the abolitionist's former home town of Rochester, New York. The mural depicts Douglass in the later years of his life. It had been destoyed by 2014.

Picturing Our Dreams is by incarcerated youth at the Monroe Correctional Facility in Rochester, New York. The mural was created in collaboration with a New York State Library Centre writer, visual artist and Rochester School District teachers. The ideology behind the mural was that inmates could communicate the idea that there is freedom and knowledge inside the jail system. In the centre of the mural, a heart with many key-holes floats around the corresponding keys, and above are the faces of the abolitionists Harriet Tubman and Frederick Douglass, as well as Barack Obama and Dr. Martin Luther King Jr.

As part of a Rochester WALL\THERAPY mural project in 2013, muralist Lunar New Year used Trayvon Martin, a young Frederick Douglass, and a local resident called Christopher to depict three possible paths of African American manhood in his mural I Am/Yo Soy. The young boy on the edge of the mural pleads to the North Star in the sky in a position that echoes Josiah Wedgwood’s famous 18th-century "Am I Not a Man and a Brother" medallion. An older version of Douglass then sits on the right side on the mural, as the only figure beyond the real and painted chain link fences.Lunar New Year, who is an Ecuadorian American Newark-based artist, explained that the mural is about “the history of institutionalized injustice in the USA… Injustice forged Frederick Douglass’s character, robbed Trayvon Martin of his life and [it] is up to us, to dictate what future awaits for young 7 year old Christopher from Rochester.”