This mural was painted in the Bronx, New York City by an unnamed artist and depicts Frederick Douglass in the later years of his life, and the phrase "Education is the pathway to freedom." it had been destroyed by 2016.

This mural was created by Harper Leich in Asheville, North Carolina in 2012 but had been destroyed by 2016. It includes the faces of Frederick Douglass, Maya Angelou, and George Washington Carver.

In 2009, Wardell McClain created a mural on South Champlain Avenue in Chicago, Illinois titled Sim's Corner Wall of Respect, that took its inspiration from the 1967 mural, Wall of Respect. It includes the faces of the abolitonists Frederick Douglass, Harriet Tubman, and Sojourner Truth as well as Martin Luther King Jr., Jesse Jackson, Malcolm X, Harold Washington, Elijah Muhammad, Nelson Mandela, Michael Jordan, Coretta Scott King, Marcus Garvey and Booker T. Washington.   

Picturing Our Dreams is by incarcerated youth at the Monroe Correctional Facility in Rochester, New York. The mural was created in collaboration with a New York State Library Centre writer, visual artist and Rochester School District teachers. The ideology behind the mural was that inmates could communicate the idea that there is freedom and knowledge inside the jail system. In the centre of the mural, a heart with many key-holes floats around the corresponding keys, and above are the faces of the abolitionists Harriet Tubman and Frederick Douglass, as well as Barack Obama and Dr. Martin Luther King Jr.

In 2000, muralist Gary Mullen created a mural that depicts how abolitionist Fredrick Douglass learned to read. It is located in the city of Baltimore, where the abolitionist spent the formative years of his life as a slave, and where he taught himself to read. Titled Young Frederick Douglass’ Quest to Read, the mural was created  bring pride to the residents of the Latrobe Homes area of north Baltimore. After reading Narrative of the Life of Frederick Douglass, the story stayed with Mullen, and when asked by the Brentwood Village Initiative to propose a mural design, the story of Douglass’ life in Baltimore was the perfect subject. The panel scenes depict Douglass’ master, Hugh Auld, scolding his wife, Sophia, for assisting Douglass to read—an illegal act at the time; Douglass trading Sophia Auld’s bread to hungry white children in exchange for reading lessons; Douglass challenging children to write as well as he does; and 12 year-old Douglass discovering the meaning of abolition. Mullen created the mural to emphasise the importance of education to the African American community in Baltimore, and local residents have received it enthusiastically, “It’s not everyday you get a mural like this in your community,” committee organiser, Patrick Lee said.

As part of a Rochester WALL\THERAPY mural project in 2013, muralist Lunar New Year used Trayvon Martin, a young Frederick Douglass, and a local resident called Christopher to depict three possible paths of African American manhood in his mural I Am/Yo Soy. The young boy on the edge of the mural pleads to the North Star in the sky in a position that echoes Josiah Wedgwood’s famous 18th-century "Am I Not a Man and a Brother" medallion. An older version of Douglass then sits on the right side on the mural, as the only figure beyond the real and painted chain link fences.Lunar New Year, who is an Ecuadorian American Newark-based artist, explained that the mural is about “the history of institutionalized injustice in the USA… Injustice forged Frederick Douglass’s character, robbed Trayvon Martin of his life and [it] is up to us, to dictate what future awaits for young 7 year old Christopher from Rochester.”

A teacher at North Lawndale College Preparatory Charter High School, Katie Bordner, created this mural with her students in 2012. It depicts the abolitionist Frederick Douglass, a mother and child and an African backdrop. 

In 1988, Mike Alewitz designed and began to direct the creation of Pathfinder Mural in New York City’s West Village. The mural, measuring 79 x 85 feet, was an international collaboration of 80 artists from 20 different countries including Argentina, Canada, Iran, New Zealand, Nicaragua and South Africa. At its dedication, it was hailed as one of the largest political murals in the world. In 1987, Alewitz had approached the leaders of the Socialist Workers Party (SWP), of which he was a member, and proposed that Pathfinder Press sponsored a mural for its Charles Street building. The party approved both the project and his concept of the mural: a celebration of the revolutionary struggles in Cuba, Grenada, Nicaragua and South Africa, as well as in America. The central image of the mural is a large red printing press. The faces of Fidel Castro, Che Guevara, Malcolm X, Karl Marx, and Nelson Mandela loop around it. The abolitionists Frederick Douglass, Harriet Tubman and Sojourner Truth also feature. During the creation of Pathfinder Mural, the National Endowment for the Arts withdrew funding from several controversial projects, prompting a debate on free speech and censorship. For the first few months of this mural's creation, work continued without incident. But in 1989, Patrick Buchanan, a conservative commentator, vilified the mural in the Washington Times, calling it a “six-story shrine to communism, a Marxist Mount Rushmore in Greenwich Village." As the mural neared completion, the dialogue between Alewitz and the SWP started to break down. Alewitz was blocked from attending the mural dedication ceremony on November 19, 1989. During December, vandals threw glass bottles filled with white paint at the mural. In 1996, the mural was removed in order to repair cracks in exterior wall of the Pathfinder building, and by 2003, the building on which Pathfinder Mural was housed was sold for around $20 million.

In 1990, an unnamed artist completed a mural inside Douglass High School in Baltimore. The mural was in a corridor and depicted black and white scenes of slavery in the background, and a colour version of the abolitionist Frederick Douglass in the foreground.

In 2012, Mexican muralist Luis Zarate created the mural Underground Railroad on Bay Street in Sodus Point, Wayne County in upstate New York. Sponsored by the Neighborhood Association of Sodus Point, the mural depicts the involvement of Sodus Point in the Underground Railroad of the 1850s. Captain George Garlock, who captained the ship Free Trader out of Sodus Point and picked up runaway slaves on his way to Canada, is depicted in the centre of the mural on the boat between the black antislavery leaders Harriet Tubman and Frederick Douglass. On July 14, 2012, a dedication ceremony revealed a plaque was mounted below the mural that reads: “This mural depicts a scene of the Underground Railroad. From stories passed down there were several safe houses in this area that were used to harbor 'Freedom Seekers.' These included the old Cohn Farm and the old Sodus Fruit Farm and what is now Maxwell Creek B & B and Silver Waters B & B. Sometimes a schooner, out of the old Sodus Point ore dock, would pick up slaves on its way to Canada."

In 1999, artist Christopher Wynter created a mosaic installation at the Cathedral Parkway subway station in Harlem. He explained that the 3-part mosaic series titled Migrations “present the ideas of uprooting, migration, and progress in symbolic form." The installation features Frederick Douglass and was placed in the subway station that runs underneath Frederick Douglass Boulevard.

In 1968, after the success of Chicago’s Wall of Respect in 1967, muralist Leroy White painted Wall of Respect/Up You Mighty Race in St. Louis, Missouri. The mural was self-sponsored. After seeing Chicago’s Wall of Respect in Ebony, muralists in St. Louis were inspired to create public art in the Carr Square area of the city. The mural was completed by a coalition of individuals from civil rights groups, including CORE, ACTION, and the Zulu 1200s. It displayed a pantheon of black heroes, including the antislavery leaders Frederick Douglass, Malcolm X, Martin Luther King Jr., and Marcus Garvey. The mural quickly became a hub of black activism—bringing together artists, performers and political figures in a series of concerts and rallies at the site. But it was vandalised during the 1970s, and its building was razed in the 1980s. 

E Pluribus Unum, “Out of Many, One,” was a mural created by Lewis Lavoie in 2012. Described as a snapshot of America, the mural brings together 50 different stories from American history, celebrating a diverse past. Located in South Jordan City’s central City Hall building, the mural is a collage of narratives such as ‘The Abolitionist Movement,’ ‘the Civil War,’ ‘The Creation of the New Media’ and ‘Westward Expansion’ for example. 

In 1976, the Mexican muralist Manuel Martinez created a mural at Auraria College titled Races of the Student Population. It depicts the antislavery leader Frederick Douglass alongside figures of the Black Power Movement including Bobby Seale, and figures and symbols of the African diaspora.  

Titled A Man and His Struggles, this mural by Magic Fingers is in the Oak Park area of Chicago and depicts the first African American mayor of the city, Harold Washington, alongside Martin Luther King Jr., Jesse Jackson, and the antislavery leader Frederick Douglass. In 2016, artists updated the mural, to add the Pan-African flag along its bottom edge.

In Plano, Texas, artists Lynne Chinn and Shug Jones created a mosaic mural titled Tracks of Our Past and Future. Made in 2006, the mural is 75 feet long and celebrates the African American community of Plano, Texas. At the centre of the mural is the antislavery leader Frederick Douglass. 

In 1997, a muralist working for the Old Town Development Board completed a mural called Paintin’ the Town on North Loudoun Street in Winchester, Virginia. It includes a depiction of Douglass during the later period of his life. It had now been destroyed.

In 2014, muralist Maryanna Donnelly created this pop art style mural at the Frederick Douglass Academy Elementary School in Los Angeles.

Brandan Odums’ murals are unusual because they tend to be off-limits to the public. One of the few muralists to reclaim dilapidated and abandoned building spaces as canvasses after Hurricane Katrina, Odums created a series of graffiti murals that aimed to inspire and provoke audiences. Although conscious of legal repercussions, Odums believed he had “a responsibility to influence people. If I see there’s a problem with a property that’s been sitting there for eight years, then I’m going to solve it within my own brain.” Turning a site of neglect into a site of pride, Odums used the Florida Housing Development in the Ninth Ward as his canvas for #projectbe, filling it wall-to-wall with portraits and quotations from figures that include the antislavery leader Frederick Douglass, Huey P. Newton, Nina Simone and James Baldwin. His artwork was deemed illegal due to his trespassing on private property. It was only seen in person by handful of visitors. After #projectbe ended, Odums embarked on a larger project at Degaulle Manor – a 360-unit apartment block. After speaking with the owner of the property, Odums was granted permission to temporarily use the building and invite the public. This project was called Exhibit BE. Around 35 street artists assisted and turned the abandoned building into one of the largest street exhibitions in the south, with 30,000 people visiting Exhibit BE in three months. The second mural of Douglass is from this exhibition. 

In 1970, a group of seven black UCLA art students created a mural titled The Black Experience on the first floor of the Ackerman Student Union building. The mural, which measures 10 feet by 27 feet, was obscured for 20 years by a false wall erected in front of it during building renovations in 1992. Then in 2013, the mural was restored. “It was important in 1970, as it is today, to address issues of racial disparity on the UCLA campus,” one of the artists, Helen Singleton said. “Our mission in creating ‘The Black Experience’ mural was to expand and enhance that effort with a visual representation of the history and experience of African Americans in the United States.” The seven art students, Helen Singleton, Marian Brown, Neville Garrick, Andrea Hill, Jane Staulz, Joanne Stewart and Michael Taylor, are all depicted in the mural, alongside silk-screened graphics of the antislavery leaders Frederick Douglass and Harriet Tubman, alongside Martin Luther King Jr., Malcolm X, Bobby Seale, Huey P. Newton, Muhammad Ali, and Angela Davis. “We learned a lot about our history by exploring what images to use,” said Garrick, who was a freshman from Jamaica when he participated in the art project. In 2012, the effort to uncover the mural gained momentum after members of the Afrikan Student Union brought the mural to the attention of the Associated Students UCLA board of directors. At the unveiling in 2013, both Singleton and Garrick were guests of honour, along with activist Angela Davis.