In 1998, at the height of gang related murders in the city of Boston, Jameel Parker was commissioned to paint a mural by Gang Peace, a not-for-profit, street-based programme seeking to reduce the number of murders in Boston by redirecting youths into education and career-oriented activities. In 1992, around 600 local youths between the ages of 8 and 23 participated in Gang Peace programmes. Parker’s mural, titled All in the Same Gang, was painted in Boston and became a monument to those who had died as a result of gang crime. During its creation, on the corner of the street where the mural was painted – Blue Hill Avenue and Floyd Street – a young boy named Dominic Mount was murdered. Given the immediate community outcry following his death, Parker dedicated the mural to Mount and placed his name alongside heroes of Black history; Frederick Douglass, W.E.B. Du Bois, Malcolm X and Elijah Muhammad. By 2016, the portraits of the African American male leaders had faded and the mural had changed to now include four black women, includng abolitionist Harriet Tubman.

In 1860, Frederick Douglass took to the stage at Boston's African Meeting House to give his speech, “A Plea for Free Speech in Boston.” Muralists Deborah Browder and Heidi Schork transcribed words from the speech onto their mural at Hammond and Tremont Street. “Liberty is meaningless when the right to utter one’s thoughts and opinions has ceased to exist,” Douglass pronounced in 1860. Three years later, in the same Meeting House on Joy Street, Beacon Hill, African American soldiers, including two of Douglass’ sons, were recruited into the Fifty-fourth Regiment of the Massachusetts Infantry under the leadership of Colonel Robert Gould Shaw.

In 1970, Eugene Eda Wade painted the Wall of Meditation on the exterior façade of the Olivet Community Center. Malcolm X and Martin Luther King Jr. anchor the middle of the mural, and are surrounded by Egyptian figures on the left, and enslaved figures breaking free from their chains on the right.    

In 2014, Rochester's Shawn Dunwoody created a mural on the Interstate 490 bridge over West Main Street. It depicts the abolitionist Frederick Douglass, as well as Susan B. Anthony, Nathaniel Rochester and Austin Steward - all famous Rochester figures

In 1976, Eugene Eda Wade created a mural at Howard University  in Washington D.C. The mural depicts the abolitionists Sojourner Truth and Nathaniel Turner attempting to break chains, as well as the abolitionists Frederick Douglass and Harriet Tubman, and leaders Malcolm X and Martin Luther King Jr. The mural has now been destroyed. 

In 2008, muralist K. Fitch painted a mural of Frederick Douglass in the abolitionist's former home town of Rochester, New York. The mural depicts Douglass in the later years of his life. It had been destoyed by 2014.

In 2010, muralist Michael Kirby created a Maryland mural titled Paradise that depicts scenes of American progress. It includes the abolitionist Frederick Douglass and other historical figures.

G. Byron Peck created this mural in Washington D.C. on the side of a boutique hotel called the Swiss Inn. In 2002, the mural was lost from public view when a luxury apartment complex was built next door, against the mural wall. The image depicts multiple stages of Frederick Douglass’ life against the backdrop of the American flag. In the 1990s, Peck became well-known in Washington D.C. after covering more than 300,000 square feet of the city's walls with his murals. Peck is now the founder, artistic firector and lead artist for all City Arts murals in the D.C. area.

Titled Our Brothers and Sisters, this mural depicts figures of black history, including the abolitionist Frederick Douglass and also Harold Washington, Martin Luther King Jr., Booker T. Washington, Malcolm X, W.E.B. Du Bois, and Louis Armstrong.

An unknown artist painted this mural in Harlem, New York City, on the facade of Dining Heritage. It depicts the abolitionists Frederick Douglass and Harriet Tubman, as well as Martin Luther King Jr., Rosa Parks, Jesse Jackson and Malcolm X. It was destroyed in 2015.

Painted in 2012 by MTC Studio, the mural depicts the black abolitionist Frederick Douglass shaking hands with President Abraham Lincoln. An older version of Douglass is offset to the right side of the mural. The mural site is adjacent to the Frederick Douglass National Historic Site in Anacostia, Washington D.C.

In 1970, John Pitman Weber of the Chicago Public Art Group created a mural on the wall of the Christopher Settlement House on the north side of Chicago. The mural faces a children’s playground in a predominantly white working-class area of the city and according to Weber, the neighbourhood’s anxiety regarding racial tensions in the community only emerged during the creation of the mural and related discussions with local residents. Working together, Weber and the local residents agreed that the racial concerns needed to be surfaced, and the mural would serve this purpose. It depicts narrative scenes across the wall, including daggers and guns held by both black and white individuals, black hands in handcuffs under the phrase “free all political prisoners,” (something that the Black Panther Party was pushing for in the 1960s and 1970s), and a black hand shaking a white hand under the faces of Frederick Douglass and the radical white abolitionist John Brown, who are both identified on the mural as Freedom Fighters. The mural had been destroyed by the late 20th century.

In 2015, muralists David Fichter, Yetti Frenkel and Joshua Winer created a 17-foot, 3 storey mural titled Central Square Mural in the city of Lynn, Massachusetts. With input from local residents and schoolchildren, the muralists created a historic panoramic at 25 Exchange Street. Assembled in two phases, the first phase entailed artists working with students from Lynn Middle and High schools to create a mosaic arch about contemporary life in Lynn. The second phase focused on the history of the city. This section depicts the shoe industries of the 19th century, labor unrest, burning factories, Hiram Marble digging for buried treasure in Lynn Woods’ Dungeon Rock, astronomer Maria Mitchell, poet Vincent Ferrini, and, assuming a central position in the mural, the abolitionist Frederick Douglass.The mural was funded by the New England Foundation for the Arts and the Massachusetts Cultural Council.

In 2006, muralist Joseph Tiberino, along with his sons Gabe and Raphael, painted Wall of Black Heroes for the African American Museum of Philadelphia. When creating the mural, the idea was to provide a portable piece of work that would later be housed in the streets. Measuring 4ft by 12ft, the mural was created on such a scale so as to provide the audience with the sense that the figures of history were life-size. The mural takes the audience on a historical journey, starting with a self-emancipating shackled slave, then moving to the abolitionists Frederick Douglass andHarriet Tubman, then Angela Davis and Malcolm X, Spike Lee, Paul Robeson, Louis Armstrong and Martin Luther King Jr. The mural is now on the side of the Municipal Services Building next to City Hall.

This mural was painted in the Bronx, New York City by an unnamed artist and depicts Frederick Douglass in the later years of his life, and the phrase "Education is the pathway to freedom." it had been destroyed by 2016.

This mural was created by Harper Leich in Asheville, North Carolina in 2012 but had been destroyed by 2016. It includes the faces of Frederick Douglass, Maya Angelou, and George Washington Carver.

In 2009, Wardell McClain created a mural on South Champlain Avenue in Chicago, Illinois titled Sim's Corner Wall of Respect, that took its inspiration from the 1967 mural, Wall of Respect. It includes the faces of the abolitonists Frederick Douglass, Harriet Tubman, and Sojourner Truth as well as Martin Luther King Jr., Jesse Jackson, Malcolm X, Harold Washington, Elijah Muhammad, Nelson Mandela, Michael Jordan, Coretta Scott King, Marcus Garvey and Booker T. Washington.   

Picturing Our Dreams is by incarcerated youth at the Monroe Correctional Facility in Rochester, New York. The mural was created in collaboration with a New York State Library Centre writer, visual artist and Rochester School District teachers. The ideology behind the mural was that inmates could communicate the idea that there is freedom and knowledge inside the jail system. In the centre of the mural, a heart with many key-holes floats around the corresponding keys, and above are the faces of the abolitionists Harriet Tubman and Frederick Douglass, as well as Barack Obama and Dr. Martin Luther King Jr.

In 2000, muralist Gary Mullen created a mural that depicts how abolitionist Fredrick Douglass learned to read. It is located in the city of Baltimore, where the abolitionist spent the formative years of his life as a slave, and where he taught himself to read. Titled Young Frederick Douglass’ Quest to Read, the mural was created  bring pride to the residents of the Latrobe Homes area of north Baltimore. After reading Narrative of the Life of Frederick Douglass, the story stayed with Mullen, and when asked by the Brentwood Village Initiative to propose a mural design, the story of Douglass’ life in Baltimore was the perfect subject. The panel scenes depict Douglass’ master, Hugh Auld, scolding his wife, Sophia, for assisting Douglass to read—an illegal act at the time; Douglass trading Sophia Auld’s bread to hungry white children in exchange for reading lessons; Douglass challenging children to write as well as he does; and 12 year-old Douglass discovering the meaning of abolition. Mullen created the mural to emphasise the importance of education to the African American community in Baltimore, and local residents have received it enthusiastically, “It’s not everyday you get a mural like this in your community,” committee organiser, Patrick Lee said.

As part of a Rochester WALL\THERAPY mural project in 2013, muralist Lunar New Year used Trayvon Martin, a young Frederick Douglass, and a local resident called Christopher to depict three possible paths of African American manhood in his mural I Am/Yo Soy. The young boy on the edge of the mural pleads to the North Star in the sky in a position that echoes Josiah Wedgwood’s famous 18th-century "Am I Not a Man and a Brother" medallion. An older version of Douglass then sits on the right side on the mural, as the only figure beyond the real and painted chain link fences.Lunar New Year, who is an Ecuadorian American Newark-based artist, explained that the mural is about “the history of institutionalized injustice in the USA… Injustice forged Frederick Douglass’s character, robbed Trayvon Martin of his life and [it] is up to us, to dictate what future awaits for young 7 year old Christopher from Rochester.”