Wilberforce House Museum is one of the world's oldest slavery museums. It opened in 1906 after the building, the house where leading abolitionist William Wilberforce was born, was bought by the Hull Corporation to preserve it for reasons of learning and of civic pride. Initially a local history museum, at the centre of Hull's historic High Street, the collections soon expanded through public donations and, unsurprisingly, these donations focussed heavily on items relating to Wilberforce. Today the museum and its collections are owned by Hull City Council and managed by Hull Culture and Leisure Limited. It forms part of Hull's 'Museums Quarter' alongside museums on transport, local social history and archaeology. In addition to the Wilberforce displays, the museum also features period room settings, silver, furniture and clocks, as well as a gallery exploring the history of the East Yorkshire Regiment.

The galleries at Wilberforce House Museum tell many different stories. An exploration of the history of the house welcomes visitors into the museum, followed by displays about William Wilberforce from his childhood, to his work and his family life. These galleries have examples of costume, books, domestic items and even the 1933 Madame Tussauds wax model of Wilberforce himself. Up the grand cantilever staircase, installed by the Wilberforce family in the 1760s, the displays continue. Here they look at the history of slavery and the origins of the British transatlantic slave trade. One gallery contains items that illustrate the richness of African culture prior to European involvement, dispelling the traditional myth that Africa was empty and uncivilised before the intervention of the Western world. Following that, the exhibition narrative goes on to look at the process of enslavement, the logistics of the trading system, the Middle Passage and slave auctions. Again, a wide range of collections are used to illustrate the informative panels. This is repeated in the displays about plantation life and resistance.

Of course no museum about William Wilberforce would be complete without an exhibition on antislavery and the abolition movement. This is extended with two galleries which look at the legacies of such a campaign in terms of modern slavery and human rights today. There are opportunities in these galleries for visitors to provide their comments and opinions, through several interactives, as well as engage with ideas as to how they can actively participate in today's campaign to end modern slavery.